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N-Acetylglutamic acid

CAS No. 1188-37-0

N-Acetylglutamic acid ( Ac-L-Glu-OH )

产品货号. M19990 CAS No. 1188-37-0

N-Acetyl-L-glutamic acid (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥332 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    N-Acetylglutamic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    N-Acetyl-L-glutamic acid (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS).
  • 产品描述
    N-Acetyl-L-glutamic acid (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea but rather accumulated in the blood leading to the condition called Type I hyperammonemia.
  • 同义词
    Ac-L-Glu-OH
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1188-37-0
  • 分子量
    189.17
  • 分子式
    C7H11NO5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:200 mM
  • SMILES
    CC(=O)N[C@@H](CCC(O)=O)C(O)=O
  • 化学全称
    acetyl-L-glutamic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Tavazzi B et al. Simultaneous high performance liquid chromatographic separation of purines pyrimidines N-acetylated amino acids and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism. Clin Biochem. 2005 Nov;38(11):997-1008.
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